Colon Studier / Tarmcancer

1 Recruiting
A Prospective Study for the Assessment of Recurrence Risk in Stage II Colon Cancer Patients Using ColoPrint

Condition: Colon Cancer
Intervention:

Completed
Mangafodipir as an Adjunct to FOLFOX6 Chemotherapy in Colon Cancer Stage Dukes’ C

Conditions: Chemotherapy;   Colon Cancer
Interventions: Drug: Mangafodipir;   Drug: Placebo treatment (0.9% NaCl)

Completed
MOSAIC – Multicenter International Study of Oxaliplatin/ 5FU-LV in the Adjuvant Treatment of Colon Cancer

Condition: Colonic Neoplasms
Intervention: Drug: Oxaliplatin (SR96669)

Completed
Safety Study of 90Y-hMN14 to Treat Colorectal Cancer

Conditions: Colorectal Cancer;   Colon Cancer;   Rectal Cancer;   Colorectal Neoplasms;   Colorectal Carcinoma;   Colorectal Tumor
Intervention: Drug: hMN14 (labetuzumab)

Active, not recruiting
Surgery With or Without Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

Conditions: Colorectal Cancer;   Metastatic Cancer
Interventions: Drug: FOLFOX regimen;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Procedure: adjuvant therapy;   Procedure: conventional surgery;   Procedure: neoadjuvant therapy

Completed
Microarray Analysis for Human Genetic Disease

Conditions: Breast Neoplasm;   Hereditary Neoplastic Syndrome;   Melanoma;   Ovarian Neoplasm
Intervention:

Completed
Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer

Conditions: Colorectal Neoplasms;   Colonic Neoplasms;   Rectal Neoplasms
Intervention: Drug: Vatalanib

Recruiting
ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Subjects With KRAS Wild-Type Metastatic Colorectal Cancer

Condition: Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab (Erbitux);   Drug: Panitumumab (Vectibix)

Completed
Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.

Conditions: Colorectal Neoplasms;   Colonic Neoplasms;   Rectal Neoplasms
Intervention: Drug: Vatalanib

10 Active, not recruiting
Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer

Conditions: Colorectal Cancer;   Metastatic Cancer
Interventions: Biological: bevacizumab;   Drug: FOLFOX regimen;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Procedure: conventional surgery;   Procedure: radiofrequency ablation

11 Completed
Preoperative NSAID to Colorectal Cancer Patients

Condition: Colorectal Cancer
Intervention: Drug: Indomethacin, celecoxib, esomeprazole

12 Recruiting
Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.

Condition: Patients With Previously Untreated Cancer in Colon or Rectum
Interventions: Drug: bevacizumab, erlotinib;   Drug: bevacizumab;   Drug: low dose capecitabine

13 Completed
Enzastaurin for Patients With Metastatic Colorectal Cancer

Condition: Colonic Neoplasms
Intervention: Drug: Enzastaurin HCl

14 Active, not recruiting
A Study to Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer

Condition: Colorectal Cancer
Interventions: Drug: lenalidomide, cetuximab;   Drug: lenalidomide

15 Active, not recruiting
A Study to Evaluate the Efficacy of Bevacizumab in Combination With Tarceva for Advanced Non-Small Cell Lung Cancer

Condition: Non-Small Cell Lung Cancer
Interventions: Drug: bevacizumab;   Drug: erlotinib HCl;   Drug: placebo

16 Completed
Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL)

Condition: Osteoporosis
Interventions: Drug: lasofoxifene;   Other: placebo

17 Completed
Study of Capecitabine and Oxaliplatin in Combination With Radiotherapy in Patients With Unresectable Gastro-Intestinal Cancer

Conditions: Stomach Cancer;   Gall Bladder Cancer;   Bile Ductus Cancer;   Pancreas Cancer;   Colorectal Cancer
Intervention: Other: oxaliplatin, capecitabine, radiotherapy

18 Recruiting
Treatment Strategies for Primarily Generalized Colorectal Cancer

Condition: Colorectal Cancer
Intervention: Procedure: Chemotherapy and surgery

19 Active, not recruiting
Oxaliplatin, Capecitabine, and Radiation Therapy With or Without Cetuximab in Treating Patients Undergoing Surgery for High-Risk Rectal Cancer

Condition: Colorectal Cancer
Interventions: Biological: cetuximab;   Drug: capecitabine;   Drug: oxaliplatin;   Procedure: adjuvant therapy;   Procedure: conventional surgery;   Procedure: neoadjuvant therapy;   Radiation: radiation therapy

20 Recruiting
The Northern-European Initiative on Colorectal Cancer

Condition: Colorectal Cancer
Intervention: Procedure: Colonoscopy

21 Active, not recruiting
Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in theTreatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen

Conditions: Colorectal Neoplasms;   Neoplasm Metastasis
Interventions: Drug: Aflibercept (AVE0005);   Drug: Placebo

22 Active, not recruiting
Cetuximab Combined With Irinotecan in First-Line Therapy for Metastatic Colorectal Cancer (CRYSTAL)

Condition: EGFR-Expressing Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab, 5-Fluorouracil, Folinic acid, Irinotecan;   Drug: 5-Fluorouracil, Folinic acid, Irinotecan

23 Completed
A Study of Xeloda (Capecitabine) as a First-Line Therapy in Patients With Metastatic Colorectal Cancer

Condition: Colorectal Cancer
Interventions: Drug: capecitabine [Xeloda];   Drug: Oxaliplatin;   Drug: Leucovorin;   Drug: 5 FU;   Drug: Avastin

24 Active, not recruiting
XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer

Condition: C04.588.274.476.411.307
Interventions: Drug: Oxaliplatin (Eloxatin);   Drug: Capecitabine (Xeloda)

25 Active, not recruiting
Panitumumab Plus FOLFIRI in First-line Treatment of Metastatic Colorectal Cancer

Condition: Metastatic Colorectal Cancer
Intervention: Drug: panitumumab and FOLFIRI

26 Active, not recruiting
Comparison of Treatment Effect of Chemotherapy With Panitumumab to Chemotherapy Alone

Condition: Metastatic Colorectal Cancer
Interventions: Drug: FOLFIRI;   Drug: Panitumumab

27 Completed
Study Of FOLFIRI Chemotherapy With Or Without Sunitinib In Patients With Metastatic Colorectal Cancer

Condition: Colorectal Neoplasms
Interventions: Drug: 5 fluorouracil;   Drug: irinotecan;   Drug: levo- leucovorin;   Drug: sunitinib;   Drug: placebo

28 Recruiting
Phase I/II Combination With Irinotecan- Erbitux

Condition: Metastatic Colorectal Cancer (MCRC)
Interventions: Drug: Cetuximab;   Drug: Irinotecan;   Drug: Brivanib;   Drug: Brivanib Placebo

29 Active, not recruiting
Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases

Conditions: Liver Metastases;   Colorectal Neoplasms;   Neoplasm Metastasis;   Neoplasm Recurrence, Local
Interventions: Drug: Talaporfin sodium;   Procedure: Percutaneous placement of device in liver metastases;   Device: Interstitial light emitting diodes;   Drug: FOLFOX4 OR FOLFIRI regimen

30 Recruiting
FLOX + Cetuximab (Erbitux®) for Patients With Metastatic Colorectal Cancer and Wild Type K-RAS Tumor

Condition: Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab (Erbitux);   Drug: Oxaliplatin (Eloxatin) + Fluorouracil + folinic acid

31 Recruiting
Health Economic Evaluation of Primovist-enhanced Liver MRI

Conditions: Colorectal Neoplasms;   Neoplasm Metastasis
Interventions: Procedure: Primovist MRI;   Procedure: Extracellular contrast media (ECCM) MRI;   Procedure: Contrast-enhanced CT

32 Recruiting
Safety Study of DNA Vaccine Delivered by Intradermal Electroporation to Treat Colorectal Cancer

Condition: Colorectal Cancer
Interventions: Biological: tetwtCEA DNA (wt CEA with tetanus toxoid Th epitope);   Device: Derma Vax (electroporation device);   Biological: GM-CSF;   Drug: Cyclophosphamide

33 Completed
Study of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal Cancer

Condition: Colorectal Cancer
Interventions: Drug: cetuximab;   Drug: Irinotecan

34 Completed
Has Results
Comparing Irinotecan and 5 FU/FA To 5-FU/FA After Resection Of Liver Metastases For Colorectal Cancer

Conditions: Colorectal Neoplasms;   Liver Neoplasms
Interventions: Drug: Irinotecan + 5 FU + folinic acid;   Drug: Folinic Acid + 5 FU

35 Active, not recruiting
A Study of Avastin (Bevacizumab) Plus Crossover Fluoropyrimidine-Based Chemotherapy in Patients With Metastatic Colorectal Cancer.

Condition: Colorectal Cancer
Interventions: Drug: bevacizumab [Avastin];   Drug: AIO-IRI, FOLFIRI, CAPIRI or XELIRI;   Drug: FUFOX, FOLFOX, CAPOX or XELOX

36 Recruiting
Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)

Condition: Adenomatous Polyposis Coli
Interventions: Drug: Celecoxib;   Drug: Placebo

37 Active, not recruiting
Chemotherapy and Avastin Followed by Maintenance Treatment With Avastin +/- Tarceva

Condition: Metastatic Colorectal Cancer
Interventions: Drug: erlotinib (Tarceva);   Drug: bevacizumab (Avastin)

38 Recruiting
Radiofrequency Ablation Versus Stereotactic Radiotherapy in Colorectal Liver Metastases

Conditions: Colorectal Carcinoma;   Liver Metastases;   Efficacy;   Toxicity
Intervention: Procedure: SBRT or RFA